I've run a garage and built engines for 30 years. I guess the point I was trying to make is that you need to work with your engine builder. Get his input before you start pulling the engine.
I've seen knocks caused by bearings, rods hitting the pan, rockerarms hitting the valvecovers, collapsed skirts, wrist pins, camshaft walking back and forth, fuel pumps, lifters, loose or broke dampners, loose or cracked flywheels, bad torque convertors, and a lot of other strange malodies. I know that if a customer had problems with one of my engines, I'd like to hear and check the symptoms before I started taking the engine apart. It's a bad comparison, but would you want to go to a doctor, say "I hurt" and expect him to start treating or operating on you with no other information?
Sometimes a little communication before action saves a lot of stress and headaches.
.0000002 worth,
Larry T
BTW, I'd drive 20 miles in a heartbeat to listen to an engine I built, if the customer had problems or wasn't satisfied with the engine.